Short-Chain Enoyl-CoA Hydratase Mediates Histone Crotonylation and Contributes to Cardiac Homeostasis. Circulation. 2021 Tang X, Chen XF, Sun X, Xu P, Zhao X, Tong Y, Wang XM, Yang K, Zhu YT, Hao DL, Zhang ZQ, Liu DP, Chen HZ. 刘德培, 29.69, A. [ PubMed ]

Role of IgE-FcεR1 in Pathological Cardiac Remodeling and Dysfunction. Circulation. 2021 Zhao H, Yang H, Geng C, Chen Y, Pang J, Shu T, Zhao M, Tang Y, Li Z, Li B, Hou C, Song X, Wu A, Guo X, Chen S, Liu B, Yan C, Wang J. 王婧, 29.69, A. [ PubMed ]

IL-2 regulates tumor-reactive CD8+ T cell exhaustion by activating the aryl hydrocarbon receptor. Nat Immunol. 2021 Liu Y, Zhou N, Zhou L, Wang J, Zhou Y, Zhang T, Fang Y, Deng J, Gao Y, Liang X, Lv J, Wang Z, Xie J, Xue Y, Zhang H, Ma J, Tang K, Fang Y, Cheng F, Zhang C, Dong B, Zhao Y, Yuan P, Gao Q, Zhang H, Xiao-Feng Qin F, Huang B. 黄波, 25.606, A. [ PubMed ]

A Hybrid Nanogel to Preserve Lysosome Integrity for Fluorescence Imaging. ACS Nano. 2021 Zhang W, Du B, Gao M, Tung CH. 张卫奇, 15.881, A. [ PubMed ]

An unexpected role for p53 in regulating cancer cell-intrinsic PD-1 by acetylation. Sci Adv. 2021 Cao Z, Kon N, Liu Y, Xu W, Wen J, Yao H, Zhang M, Wu Z, Yan X, Zhu WG, Gu W, Wang D. 王冬来, 14.136, A. [ PubMed ]

Identification of pathogenic variants in cancer genes using base editing screens with editing efficiency correction. Genome Biol. 2021 Huang C, Li G, Wu J, Liang J, Wang X. 王晓月, 13.583, A. [ PubMed ]

A global screening identifies chromatin-enriched RNA-binding proteins and the transcriptional regulatory activity of QKI5 during monocytic differentiation. Genome Biol. 2021 Ren Y, Huo Y, Li W, He M, Liu S, Yang J, Zhao H, Xu L, Guo Y, Si Y, Zhao H, Rao S, Wang J, Ma Y, Wang X, Yu J, Wang F. 余佳, 13.583, A. [ PubMed ]

NADPH levels affect cellular epigenetic state by inhibiting HDAC3-Ncor complex. Nat Metab. 2021 Li W, Kou J, Qin J, Li L, Zhang Z, Pan Y, Xue Y, Du W. 杜文静, 13.511, A. [ PubMed ]

Cell Softness Prevents Cytolytic T-cell Killing of Tumor-Repopulating Cells. Cancer Res. 2021 Liu Y, Zhang T, Zhang H, Li J, Zhou N, Fiskesund R, Chen J, Lv J, Ma J, Zhang H, Tang K, Cheng F, Zhou Y, Zhang X, Wang N, Huang B. 黄波, 12.701, A. [ PubMed ]

YTHDF1 Promotes Gastric Carcinogenesis by Controlling Translation of FZD7. Cancer Res. 2021 Pi J, Wang W, Ji M, Wang X, Wei X, Jin J, Liu T, Qiang J, Qi Z, Li F, Liu Y, Ma Y, Si Y, Huo Y, Gao Y, Chen Y, Dong L, Su R, Chen J, Rao S, Yi P, Yu S, Wang F, Yu J. 余佳, 12.701, A. [ PubMed ]

Genome-wide analysis of pseudogenes reveals HBBP1's human-specific essentiality in erythropoiesis and implication in β-thalassemia. Dev Cell. 2021 Ma Y, Liu S, Gao J, Chen C, Zhang X, Yuan H, Chen Z, Yin X, Sun C, Mao Y, Zhou F, Shao Y, Liu Q, Xu J, Cheng L, Yu D, Li P, Yi P, He J, Geng G, Guo Q, Si Y, Zhao H, Li H, Banes GL, Liu H, Nakamura Y, Kurita R, Huang Y, Wang X, Wang F, Fang G, Engel JD, Shi L, Zhang YE, Yu J. 余佳, 12.270, A. [ PubMed ]

Cell softness regulates tumorigenicity and stemness of cancer cells. EMBO J. 2021 Lv J, Liu Y, Cheng F, Li J, Zhou Y, Zhang T, Zhou N, Li C, Wang Z, Ma L, Liu M, Zhu Q, Liu X, Tang K, Ma J, Zhang H, Xie J, Fang Y, Zhang H, Wang N, Liu Y, Huang B. 黄波, 11.598, A. [ PubMed ]

hnRNPLL controls pluripotency exit of embryonic stem cells by modulating alternative splicing of Tbx3 and Bptf. EMBO J. 2021 Wang X, Ping C, Tan P, Sun C, Liu G, Liu T, Yang S, Si Y, Zhao L, Hu Y, Jia Y, Wang X, Zhang M, Wang F, Wang D, Yu J, Ma Y, Huang Y. 黄粤、余佳, 11.598, A. [ PubMed ]

Multi-omics study of silicosis reveals the potential therapeutic targets PGD2 and TXA2. Theranostics. 2021 Pang J, Qi X, Luo Y, Li X, Shu T, Li B, Song M, Liu Y, Wei D, Chen J, Wang J, Wang C. 王辰, 11.556, A. [ PubMed ]

Elevated IgE promotes cardiac fibrosis by suppressing miR-486a-5p. Theranostics. 2021 Zhao H, Yang H, Geng C, Chen Y, Tang Y, Li Z, Pang J, Shu T, Nie Y, Liu Y, Jia K, Wang J. 王婧, 11.556, A. [ PubMed ]

ACE2 expression is regulated by AhR in SARS-CoV-2-infected macaques. Cell Mol Immunol. 2021 Lv J, Yu P, Wang Z, Deng W, Bao L, Liu J, Li F, Zhu Q, Zhou N, Lv Q, Wang G, Wang S, Zhou Y, Song J, Tong WM, Liu Y, Qin C, Huang B. 黄波, 11.53, A. [ PubMed ]

Mucins produced by type II pneumocyte: culprits in SARS-CoV-2 pathogenesis. Cell Mol Immunol. 2021 Huang B. 黄波, 11.53, A. [ PubMed ]

ADAR1 Stimulation by IFN-α Downregulates the Expression of MAVS via RNA Editing to Regulate the Anti-HBV Response. Mol Ther. 2021 Li T, Yang X, Li W, Song J, Li Z, Zhu X, Wu X, Liu Y. 刘英, 11.454, A. [ PubMed ]

Distinct uptake, amplification, and release of SARS-CoV-2 by M1 and M2 alveolar macrophages. Cell Discov. 2021 Lv J, Wang Z, Qu Y, Zhu H, Zhu Q, Tong W, Bao L, Lv Q, Cong J, Li D, Deng W, Yu P, Song J, Tong WM, Liu J, Liu Y, Qin C, Huang B. 黄波, 10.849, A. [ PubMed ]

Panoramic transcriptome analysis and functional screening of long noncoding RNAs in mouse spermatogenesis. Genome Res. 2021 Li K, Xu J, Luo Y, Zou D, Han R, Zhong S, Zhao Q, Mang X, Li M, Si Y, Lu Y, Li P, Jin C, Wang Z, Wang F, Miao S, Wen B, Wang L, Ma Y, Yu J, Song W. 宋伟、余佳, 9.043, A. [ PubMed ]

p53 transcriptionally regulates SQLE to repress cholesterol synthesis and tumor growth. EMBO Rep. 2021 Sun H, Li L, Li W, Yang F, Zhang Z, Liu Z, Du W. 杜文静, 8.807, A. [ PubMed ]

Serum Sp17 Autoantibody Serves as a Potential Specific Biomarker in Patients with SAPHO Syndrome. J Clin Immunol. 2021 You H, Dang G, Lu B, Zhang S, Li C, Wang L, Hu Y, Chen H, Zhang J, He W. 何维/张建民, 8.317, A. [ PubMed ]

A comprehensive RNA editome reveals that edited Azin1 partners with DDX1 to enable hematopoietic stem cell differentiation. Blood. 2021 Wang F, He J, Liu S, Gao A, Yang L, Sun G, Ding W, Li CY, Gou F, He M, Wang F, Wang X, Zhao X, Zhu P, Hao S, Ma Y, Cheng H, Yu J, Cheng T. 余佳, 22.113, B1. [ PubMed ]

Boosting anti-PD-1 therapy with metformin-loaded macrophage-derived microparticles. Nat Commun. 2021 Wei Z, Zhang X, Yong T, Bie N, Zhan G, Li X, Liang Q, Li J, Yu J, Huang G, Yan Y, Zhang Z, Zhang B, Gan L, Huang B, Yang X. 黄波, 14.919, B2. [ PubMed ]

Cyclic nucleotide phosphodiesterase 1C contributes to abdominal aortic aneurysm. Proc Natl Acad Sci U S A. 2021 Zhang C, Zhao H, Cai Y, Xiong J, Mohan A, Lou D, Shi H, Zhang Y, Long X, Wang J, Yan C. 王婧, 11.205, B2. [ PubMed ]